President

Jason Fang

I'm a junior at Seven Lakes HS with a focused interest in computational biology and thoracic oncology. My main research focus is thoracic oncology, especially genomics/computational biology research in NSCLC. My current research centers on two projects: identifying non-oncology drugs with viable repurposing potential in non-small cell lung cancer (NSCLC) by targeting the EGFR L858R mutation using computational tools including AutoDock and Boltz-2, and identifying FDA-approved drugs predicted to inhibit DCLK1, an understudied kinase in gastrointestinal cancers. Docking an approved-drug library against the DCLK1 kinase domain (PDB 7F3G) with AutoDock Vina, validating against known binders (ruxolitinib, DCLK1-IN-1), filtering by hinge-pose quality, and re-scoring top hits with Boltz-2 co-folding. Outside of school, I'm an active teacher volunteer for Huaxia Chinese School, earning over 280+ hours as a science teacher, Intern at the Young Lab at BCM, and a Summer Research Trainee at MD Anderson Cancer Center. My goal is to make cancer research more accessible to students just like me, and inspire my fellow peers to pursue this fight against cancer together.